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KMID : 0363420160300030078
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Journal of Korean Oriental Pediatrics
2016 Volume.30 No. 3 p.78 ~ p.96
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Review of Clinical Research on Effect of Traditional Chinese Medicine for Febrile Seizure
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Lee Bo-Ram
Lee Eun-Ju
Lee Ji-Hong
Chang Gyu-Tae
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Abstract
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Objectives: The purpose of this study is to provide clinical evidence of Korean medicine for febrile seizure by review of randomized controlled trials on the effect of TCM (traditional Chinese medicine) for febrile seizure.
Methods: We searched randomized controlled trials about TCM treatment of febrile seizure from the China National Knowledge Infrastructure (CNKI) (January 2008 to June 2016). The selected literatures were assessed by Jadad scale.
Results: 40 papers were selected from 160 studies. Analyses of selected studies indicated that the TCM treatment group has significantly higher cure rate for febrile seizure than first aid or western medicine group. The most commonly used herbs were Gardeniae Fructus (ö¼í), Uncariae Ramulus cum Uncis (ÏÉÔö), Cornus Gazeliae (çÆåÏÊÇ), Margarita (òÒñÁ), Scutellariae Radix (üÜÐÙ), Glycyrrhizae Radix (Êöõ®). The most commonly used acupoints were GV26 (ìÑñé), LI4 (ùêÍÛ), KI1 (éÀô»), GV20 (ÛÝüå). There were no serious adverse events reported from the TCM treatment group during the treatment period.
Conclusions: TCM has been shown as not only effective but also safe treatment on febrile seizure. This finding can be widely utilized in clinical practice and can form the basis for development of clinical practice guidelines in future.
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KEYWORD
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Febrile seizure, Traditional chinese medicine, Children, Randomized controlled trial, Jadad scale
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